Spatial variations in ambient ultrafine particle concentrations and risk of congenital heart defects

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Ambient temperature and congenital heart defects.

STUDY QUESTION Does maternal exposure during pregnancy to higher ambient temperature increase the risk of congenital heart defects (CHDs)? SUMMARY ANSWER Significant associations were found between maternal exposure during pregnancy to higher ambient temperature and CHDs risk especially during the cold season. WHAT IS KNOWN ALREADY From rodents to non-human primates, a teratogenic effect of...

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Paternal Occupational Exposure to Solvents and The Risk of Congenital Heart Defects in Children Using Job Exposure Matrix

Background and aims: Currently, as a result of research on laboratory animals, abundant information has been obtained on the impact of various environmental factors on the occurrence of congenital malformations, but there is still no comprehensive information on the causes of congenital heart malformations (CHD) in human populations. Congenital heart defects (CHDs) constitute the major class of...

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Risk of Congenital Heart Defects after Ambient Heat Exposure Early in Pregnancy

BACKGROUND Congenital heart defects may be environmentally related, but the association with elevated ambient temperature has received little attention. OBJECTIVES We studied the relationship between outdoor heat during the first trimester of pregnancy and risk of congenital heart defects. METHODS We carried out a retrospective cohort study of 704,209 fetuses between 2 and 8 weeks postconce...

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Congenital heart defects in chick embryos subjected to temperature variations.

• Several epidemiological studies" have shown a positive correlation between viral diseases early in pregnancy and congenital heart disease in human beings. Since viral diseases are accompanied commonly by fever, it was considered important to investigate the effect of high temperature alone on the development of the heart in chick embryos. It was also thought that incubation at low temperature...

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The Prevalence of Celiac Disease in Down syndrome Children with and without Congenital Heart Defects

Background The prevalence of celiac disease (CD) is remarkably varied in Down syndrome(DS)patientscompared with other diseases.  This study aimed to assess celiac disease prevalence in Down syndrome children with and without congenital heart defects (CHD) and its comparison with controls. Materials and Methods This case-control study was performed at a single center on 132 participants in three...

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ژورنال

عنوان ژورنال: Environment International

سال: 2019

ISSN: 0160-4120

DOI: 10.1016/j.envint.2019.104953